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Thread: Panorama The Antidepressant Story

  1. #1
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    Panorama The Antidepressant Story

    Panorama The Antidepressant Story

    https://www.bbc.co.uk/programmes/m001n39z

    Apparently, depression is not caused by a chemical imbalance, that's just quoted to sell the drugs.

    The Antidepressants were only said to be 55% successful in trials while the placebo was 40%.

    And for many people coming off them can carry terrible withdrawal symptoms.

  2. #2

    Re: Panorama The Antidepressant Story

    The trouble with them is the black market , the Health service has a part to play in regulatory standards and processes of issuing either legally or illegally sadly health workers and third parties like pharmacies are invloved.

  3. #3

    Re: Panorama The Antidepressant Story

    Quote Originally Posted by North Cardiff Blue View Post
    Panorama The Antidepressant Story

    https://www.bbc.co.uk/programmes/m001n39z

    Apparently, depression is not caused by a chemical imbalance, that's just quoted to sell the drugs.

    The Antidepressants were only said to be 55% successful in trials while the placebo was 40%.

    And for many people coming off them can carry terrible withdrawal symptoms.

    I think they are great

  4. #4

    Re: Panorama The Antidepressant Story

    My old bean had withdrawal symptoms on these. Gran did as well from old bean’s side. Don’t know what brand as I have never needed them.

    Probably should have after a bad split with a bird when I was 25, but six-eight months of alcoholism and disco biscuits did wonders for the mood lifting.

    What becomes of my liver lining in time I haven’t the foggiest. So far so good. Famous last words. Place your bets on when the wooden box is required.

    Tick tock…

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    Re: Panorama The Antidepressant Story

    Quote Originally Posted by SLUDGE FACTORY View Post
    I think they are great
    There weren't designed to be taken forever, lots of people can't manage without them, it's one long-term experiment now, and they're not sure what effect they will have on you long-term.

  6. #6

    Re: Panorama The Antidepressant Story

    Quote Originally Posted by North Cardiff Blue View Post
    There weren't designed to be taken forever, lots of people can't manage without them, it's one long-term experiment now, and they're not sure what effect they will have on you long-term.
    They said that about paracetamol

    It's the most effective first line painkiller we have

    But take too many of them and its good night

  7. #7

    Re: Panorama The Antidepressant Story

    Quote Originally Posted by North Cardiff Blue View Post
    Panorama The Antidepressant Story

    https://www.bbc.co.uk/programmes/m001n39z

    Apparently, depression is not caused by a chemical imbalance, that's just quoted to sell the drugs.

    The Antidepressants were only said to be 55% successful in trials while the placebo was 40%.

    And for many people coming off them can carry terrible withdrawal symptoms.
    Cancer drugs do not cure cancer for at least 50 percent of patients ......what do you think about that ?

    A lot of cancer drugs have extremely serious side effects .......losing all your body hair is not a symptom of cancer generally ......its the side effects of the chemotherapy

    Do you think we should have an enquiry or documentary into cancer drugs ?

    The problem with anti depressant drugs is not that they not effective for most people .....they are

    It's getting people to take them regularly in the first place and not to panic or get too worried if they get minor side effects whilst they get used to the drugs . People go on Google and on social media and listen to nonsense rather than their doctor who is a professional.

    There are people out there who are clearly unwell and need tablets and counselling but they either don't have both , just have counselling or refuse to take medication

    It's fecking insane

    It's a serious illness , people prescribed these tablets have usually had problems for years yet unlike cancer where almost everyone would take medicine to cure things ......they are wreckless and refuse tablets

    I don't have much sympathy for them

    Those that do try tablets yet struggle with side effects need to keep working with their doctor

  8. #8

    Re: Panorama The Antidepressant Story

    The odds are they are probably good although my ma and gran struggled to come off them.

    What bothers me more is the incentives baked into the system. As the old shrewd saying goes “Show me the incentive and I’ll show you the outcome”. That is to say, where there is an incentive or a motive to behave in a certain way which accrues an advantage of some kind, humans will find a loophole and generally behave in a way which accrues that advantage.

    In this case we can sensibly surmise that on a coin flip of 50/50, if your statistics are correct, it seems that 50% of depression will be cured. But two other things stand out:

    1. GPs are incentivised to issue the drugs, and are inclined to push them. Rarely do GPs discuss holistic solutions such as exercise, diet, improved social activity, volunteering, creative activities and other tools that are known to help with depression. My ma and gran never received this advice. Don’t forget, they are private practitioners (like dentists), even though they work for the NHS.

    2. Pharmaceuticals will recieve a larger profit by pushing them onto the NHS / Private doctors

    Therefore, with a push from the two above, and a clear motivation to sustain it due to incentives in the system, it is not intelligent to be a mug and assume they are all angels or that their interests are aligned to yours. But nor is it reasonable nor fair to assume they are all bent. But it is at least reasonable, and arguable, to question the ethics and the logic for issuing these drugs is correct in all cases, and for a sustained period. Because the incentives of .1 and .2 should be telling us, or more so screaming at us, to at least keep an open mind.

    Assuming a tribal “For” or “Against”, taking sides in a tribal manner, is for the arena of religion, war, politics or sport. This is a scientific subject, and therefore until all the answers and angles are clear and conclusive, it is more sensible to adopt a position of retaining an open mind.

  9. #9

    Re: Panorama The Antidepressant Story

    Really enjoying Patrick Radden Keefe, just finished Say Nothing & Chatter and have Empire of Pain: The Secret History of the Sackler Dynasty lined up to go when i finish my current book.

  10. #10
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    Re: Panorama The Antidepressant Story

    Quote Originally Posted by SLUDGE FACTORY View Post
    Cancer drugs do not cure cancer for at least 50 percent of patients ......what do you think about that ?

    A lot of cancer drugs have extremely serious side effects .......losing all your body hair is not a symptom of cancer generally ......its the side effects of the chemotherapy

    Do you think we should have an enquiry or documentary into cancer drugs ?

    The problem with anti depressant drugs is not that they not effective for most people .....they are

    It's getting people to take them regularly in the first place and not to panic or get too worried if they get minor side effects whilst they get used to the drugs . People go on Google and on social media and listen to nonsense rather than their doctor who is a professional.

    There are people out there who are clearly unwell and need tablets and counselling but they either don't have both , just have counselling or refuse to take medication

    It's fecking insane

    It's a serious illness , people prescribed these tablets have usually had problems for years yet unlike cancer where almost everyone would take medicine to cure things ......they are wreckless and refuse tablets

    I don't have much sympathy for them

    Those that do try tablets yet struggle with side effects need to keep working with their doctor
    I know nothing about it, never taken any tablets except paracetamol or Ibuprofen once or twice a year.

    I came across the programme by accident and ended up watching it. Their conclusion was it's essential for some, and may stop certain extreme cases from committing suicide, but that it appears to have been overprescribed sold on a lie, and that it's a long-term concern with the number of people that can't get off them because of heavy withdrawal symptoms.

    I think if I was on them I'd watch it to learn a bit more.

  11. #11
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    Re: Panorama The Antidepressant Story

    Quote Originally Posted by SLUDGE FACTORY View Post
    Cancer drugs do not cure cancer for at least 50 percent of patients ......what do you think about that ?

    A lot of cancer drugs have extremely serious side effects .......losing all your body hair is not a symptom of cancer generally ......its the side effects of the chemotherapy

    Do you think we should have an enquiry or documentary into cancer drugs ?

    The problem with anti depressant drugs is not that they not effective for most people .....they are

    It's getting people to take them regularly in the first place and not to panic or get too worried if they get minor side effects whilst they get used to the drugs . People go on Google and on social media and listen to nonsense rather than their doctor who is a professional.

    There are people out there who are clearly unwell and need tablets and counselling but they either don't have both , just have counselling or refuse to take medication

    It's fecking insane

    It's a serious illness , people prescribed these tablets have usually had problems for years yet unlike cancer where almost everyone would take medicine to cure things ......they are wreckless and refuse tablets

    I don't have much sympathy for them

    Those that do try tablets yet struggle with side effects need to keep working with their doctor
    If I thought I needed either and was told by a doctor, I would take whatever tablets they prescribed, I would probably research a bit first though.

  12. #12
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    Re: Panorama The Antidepressant Story

    Quote Originally Posted by Keyser Soze View Post
    The odds are they are probably good although my ma and gran struggled to come off them.

    What bothers me more is the incentives baked into the system. As the old shrewd saying goes “Show me the incentive and I’ll show you the outcome”. That is to say, where there is an incentive or a motive to behave in a certain way which accrues an advantage of some kind, humans will find a loophole and generally behave in a way which accrues that advantage.

    In this case we can sensibly surmise that on a coin flip of 50/50, if your statistics are correct, it seems that 50% of depression will be cured. But two other things stand out:

    1. GPs are incentivised to issue the drugs, and are inclined to push them. Rarely do GPs discuss holistic solutions such as exercise, diet, improved social activity, volunteering, creative activities and other tools that are known to help with depression. My ma and gran never received this advice. Don’t forget, they are private practitioners (like dentists), even though they work for the NHS.

    2. Pharmaceuticals will recieve a larger profit by pushing them onto the NHS / Private doctors

    Therefore, with a push from the two above, and a clear motivation to sustain it due to incentives in the system, it is not intelligent to be a mug and assume they are all angels or that their interests are aligned to yours. But nor is it reasonable nor fair to assume they are all bent. But it is at least reasonable, and arguable, to question the ethics and the logic for issuing these drugs is correct in all cases, and for a sustained period. Because the incentives of .1 and .2 should be telling us, or more so screaming at us, to at least keep an open mind.

    Assuming a tribal “For” or “Against”, taking sides in a tribal manner, is for the arena of religion, war, politics or sport. This is a scientific subject, and therefore until all the answers and angles are clear and conclusive, it is more sensible to adopt a position of retaining an open mind.
    The program blames big pharma really, saying that people suffer it because of a chemical imbalance was the sales ploy, they said that made people believe taking these would correct that imbalance, but the chemical imbalance was just a line that's never been proved.

  13. #13
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    Re: Panorama The Antidepressant Story

    Quote Originally Posted by North Cardiff Blue View Post
    I know nothing about it, never taken any tablets except paracetamol or Ibuprofen once or twice a year.

    I came across the programme by accident and ended up watching it. Their conclusion was it's essential for some, and may stop certain extreme cases from committing suicide, but that it appears to have been overprescribed sold on a lie, and that it's a long-term concern with the number of people that can't get off them because of heavy withdrawal symptoms.

    I think if I was on them I'd watch it to learn a bit more.
    Forgot had antibiotics too, they seem to speed up infections with no issues (for me) so would defo take again.

  14. #14

    Re: Panorama The Antidepressant Story

    Quote Originally Posted by OurManFlint II View Post
    Really enjoying Patrick Radden Keefe, just finished Say Nothing & Chatter and have Empire of Pain: The Secret History of the Sackler Dynasty lined up to go when i finish my current book.
    Sounds interesting. The sacklers are truly awful. The amount of wasted lives , death and addiction caused by them is almost limitless. I'm not religious, but if there is an afterlife, I hope they suffer absolutely terribly. Truly horrendous people

  15. #15

    Re: Panorama The Antidepressant Story

    In the short term they are a viable option.

    Unfortunately it's too easy to just prescribe these and not get to the root cause of why someone is unwell.

  16. #16

    Re: Panorama The Antidepressant Story

    Quote Originally Posted by chrisp_1927 View Post
    Sounds interesting. The sacklers are truly awful. The amount of wasted lives , death and addiction caused by them is almost limitless. I'm not religious, but if there is an afterlife, I hope they suffer absolutely terribly. Truly horrendous people
    I'm aware of them but luckily I've avoided the higher profile TV/Podcast etc around them as Keefe is a great storyteller, so looking forward to his telling of it. Say Nothing is an amazing story.

  17. #17

    Re: Panorama The Antidepressant Story

    Quote Originally Posted by North Cardiff Blue View Post
    The program blames big pharma really, saying that people suffer it because of a chemical imbalance was the sales ploy, they said that made people believe taking these would correct that imbalance, but the chemical imbalance was just a line that's never been proved.
    There isn't much money to be made in the UK once a medicine loses its patent

    Once that happens you are just given the generic tablet

    If you go into a chemist and ask for paracetamol it's 79 p

    If you go in and ask for panadol ......which is paracetamol but in a fancy packet it's 5 quid

    In America I belive that's where the gullible locals are fed the expensive ones

  18. #18

    Re: Panorama The Antidepressant Story

    Another group of pills i loved as a kid on the Northern Soul scene - drinamyl spansules or green and clears many a chemist got broken into for these little beauties.

  19. #19

    Re: Panorama The Antidepressant Story

    Quote Originally Posted by SLUDGE FACTORY View Post
    If you go in and ask for panadol ......which is paracetamol but in a fancy packet it's 5 quid

    In America I belive that's where the gullible locals are fed the expensive ones
    The US has alot more of the shelf meds, go to a big supermarket and its big business, Walmarts own brand "equate" is cheap as chips, we always buy equate ibuprofen, they come in a 500 pill tub ( was about a fiver ) same with Paracetamol

    Diphenhydramine ( sleeping pills ) are available of the shelf 1 years supply, under 10 quid
    Melatonin Gummies ( Sleeping aid ) 120 for a few quid

  20. #20

    Re: Panorama The Antidepressant Story

    Seems weird to me that we just push antidepressents as much as possible rather than making society better. It's no wonder depression rates are going up.

  21. #21

    Re: Panorama The Antidepressant Story

    Quote Originally Posted by Doucas View Post
    Seems weird to me that we just push antidepressents as much as possible rather than making society better. It's no wonder depression rates are going up.
    Anti depressants are used by wise doctors to help people with severe illness or those who havnt been helped by counselling

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