National lockdown on the way for England.Quote:
Originally Posted by the other bob wilson
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National lockdown on the way for England.Quote:
Originally Posted by the other bob wilson
Oxford AstraZeneca Vaccine approval granted
Massive news, but I just hope that people don't think it's an excuse to ignore the rules.
https://www.bbc.co.uk/news/health-55280671
Roll out begins next weekQuote:
Originally Posted by The Bloop
Good news, albeit very heavily leaked. There were a couple of particularly interesting paragraphs in the BBC story I thought - i.e.;-
"However, unpublished data suggests that leaving a longer gap between the first and second doses increases the overall effectiveness of the jab.
There was not enough clear data to approve the half-dose, full-dose idea."
Yes they had only tested the half dose on 10 people but 9 of of 10 had success. Or was it 100 people? My memory....good news though Bob particularly as after one jab it will give you decent immunity against getting it but even if you did symptoms are much less severe.Quote:
Originally Posted by the other bob wilson
Mass rollout next week for as many as possible
More than 10 in fact.....Quote:
Originally Posted by goats
Of 1,367 people given a half first dose of the vaccine followed by a full second dose, there was 90% protection against Covid-19 when compared with a control group of 1,374 people.
Lets hope Drakeford and Gethin have everything in place to get this rolled out quickly.
Key thing is this line in the Guarniad.Quote:
Originally Posted by The Bloop
"And while there are some early signs the Oxford/AstraZeneca vaccine might not only prevent people becoming seriously ill with Covid but also prevent asymptomatic infections, more data is needed to confirm such protection."
This could give the Oxford vaccine a real advantage. The Pfizer jab isn't known to prevent onward transmission so a vaccinated person would still have to exercise the social distancing rules etc in case they carry the virus with no ill-effects (thanks to the vaccine).
If the Oxford jab prevents transmission then people who can't get vaccinated for whatever reasons will also get protected as we head towards herd immunity.
Why go and ruin the good vibes with a dose of reality......:xmashehe:Quote:
Originally Posted by Hilts
This is why it’s better....Quote:
Originally Posted by Allez Allez Allez
Obviously the vaccine is great news but you have to wait a period of 12 weeks between the first and second doses to get full immunity. That means the population at large will have to continue to take precautions but the good news is that more people will be able to get vaccinated earlier. Another piece of good news is that there are sufficient quantities of the vaccine already manufactured to meet UK demand. The scientists have done their bit and now it's up to the various UK governments to roll the vaccine out and there lies a potential problem.
This kind of stuff is administrative though so I imagine it'll fall to the civil service, who are generally competent rather than our politiciansQuote:
Originally Posted by Vindec
Rates in Wales falling in last few days.
Is this due to hospitality closing. Or schools? Both?
Lets hope it continues to fall with the additional measures
https://www.walesonline.co.uk/news/w...eaths-19538614
Not sure how much faith can be put in figures over a holiday period, but the trends do seem more encouraging - it's too early yet for the latest lockdown to be having an effect yet I would have thought.Quote:
Originally Posted by Hilts
40,000 vaccines allocated to Wales from next week;-
https://www.bbc.co.uk/news/uk-wales-55496058
The downward trend continues in new cases, but an awful deaths figure to go alongside nearly a thousand in the UK yesterday;-
https://public.tableau.com/profile/p...eadlinesummary
Intensive care doctor tells it like it is:
https://www.bbc.co.uk/news/uk-55479018
Powerful stuff.
You're alright mate; I get my news from ex-rugby players, right-wing radio hosts and conspiracy theorists who are going to walk away without personal consequence if their ideas turn out to be wrong.Quote:
Originally Posted by Gofer Blue
Who's this ex rugby player you keep on mentioning?Quote:
Originally Posted by surge
As for what the doctor said, it needs a wider audience than it would have probably got on Radio 5 this morning - hopefully, it's getting plenty of listens on social media.
??? :frown:Quote:
Originally Posted by surge
Yes, disappointing that it wasn't mentioned on the BBC main news at 1.00pm. Should be compulsory listening!Quote:
Originally Posted by the other bob wilson
Pleased to see it on the main BBC News websiteQuote:
Originally Posted by Gofer Blue
My mother in law is in a Care Home.
Been told today shes having the Pfizer vaccine next week.
Bit strange as i thought there was a delay due to the logistics and now the Oxford is available. At least the home is getting done though and hopefully they are doing other places in the area as well.
Wonder how long it will take to get the 1.5 million people 50+ or with underlying conditions vaccinated? They hope to do that many a week in England dont they? But this is Wales.....
Ian Gough.Quote:
Originally Posted by the other bob wilson
Regarding the pfizer vaccines, can anyone explain what it meant by this: "The Pfizer and BioNTech covid-19 vaccine may provide some early protection, starting 12 days after the first dose, the peer reviewed results of a phase III trial have found.
The study, published in the New England Journal of Medicine,1 found that vaccine efficacy between the first and second doses was 52% (95% credible interval 29.5% to 68.4%)."
(https://www.bmj.com/content/371/bmj.m4826 posting source because I don't know if there is more up-to-date information).
It's obviously an incredibly difficult decision to make regarding how to roll-out vaccines with speed of highest importance for vulnerable people, and some protection much better than none at all.
Not quite sure what those stats refer too, I thought it was 91% after the first jab, hence Tony Bliar saying why bother with 2nd jab as it’s only another 4%? Think the 2nd will give it longevity maybe? But you can wait 12 weeks so get more people done with first one asap which makes sense.Quote:
Originally Posted by surge
Quote:
Originally Posted by the other bob wilson
You don't expect him to reveal his 'sauces' do you?
But when a doctor or whoever from some hospital or university or whatever comes on the TV or in the papers and casts doom and gloom I alwyas wonder how many the news outlet spoke to before they found one who would say what they wanted.
After all, as we know, bad news is good news for journalists.
It's saying that after the first dose 52% of people had some protection...this ranged from 29.5% to 68.4% in various trials. The second dose given within 3 weeks lifted the protection rate to 95%. Pfizer have no evidence of effectiveness using the regime the UK proposes which is the second dose within 12 weeks. Dr Chris Whitty says the first injection gives the biggest response the second dose being a booster. He is right but it's marginal...ie 52% protection first dose increasing by another 43% after the second dose.Quote:
Originally Posted by surge
The MHRA approved the drug based on the Pfizer data and they in turn have said that this was on a regime of a repeat dose within 3 weeks. Looks like in our panic to get this vaccination out asap they are willing to accept that up to half the people having it will not be protected until they get the second dose and there is no evidence that the second dose will be as effective given at 12 weeks compared to the Pfizer recommended regime of repeat in 3 weeks..
The above may not be relevant for the AZ vaccine as I've not looked at the data they have published or the dose regime used
In my opinion this sudden and cavalier change from UK chief medical officers without any scientific evidence risks messing up the whole bloody thing. Have any countries followed our lead....no way!
If you're not happy about it, you could ask the care home not to give it to her and tell them to wait for the Oxford one. :shrug:Quote:
Originally Posted by Hilts
Yes I realise that the medical standards people wouldn't agree to the 12c week wait just for political reasons, so it must be a science and knowledge based decision.Quote:
Originally Posted by goats
What does bother me is that if they use all the doses for first jabs then eventually they will have to stop giving first jabs for 12 weeks while all those people get their second jab. That's not science or political it is simple supply and demand
https://twitter.com/VictimOfMaths/st...361925632?s=19
this is a very stark difference - and northern Ireland is a fair bit lower rate than the rest of the UK.
I wonder what the reason is ?
Probably Brexit. May as well blame it, it gets the blame for everything else. But seriously, the assumption is that the Eire figures are accurate. They may not be, or may be counted differently.Quote:
Originally Posted by Rjk
I didnt say I wasnt happy with it.!Quote:
Originally Posted by xsnaggle
I know, just a wind up, sorry. I'm in that kind of mood :xmashehe: :hide:Quote:
Originally Posted by Hilts
But it did read a little bit that way. :-)
UK has 5 million doses of the Oxford vaccine available. India has 50 million doses of the Oxford vaccine available. They ordered and distributed them in anticipation of the vaccine being approved so they could hit the ground running.Quote:
Originally Posted by goats
I think thats incorrect. I think the total stockpile Oxford has is 50m doses.Quote:
Originally Posted by A Quiet Monkfish
They have 530,000 doses available with another 500,000 due next week. There isn't a stockpileQuote:
Originally Posted by Hilts
The world's biggest producer of vaccines, has already stockpiled about 50 million doses, enough for 25 million people. India will be the first priority for the delivery of the AstraZeneca-Oxford vaccine, Adar Poonawalla, chief executive officer, Serum Institute of India, earlier mentioned. "The COVID-19 vaccine will be distributed initially in India, then we will look at the COVAX countries which are mainly in Africa. Our priority is India & COVAX countries," Poonawalla said.Quote:
Originally Posted by lisvaneblue
????
Yhose figures could possibly be quite correct for the serum that is being manufactured in India, but as the serum for UK is appparently being manufactured in Wrexham I'll try not to worry about it too muchQuote:
Originally Posted by A Quiet Monkfish
Just more scaremongering.
Professor Sarah Gilbert stated on Sky News a few days ago that enough of the Oxford vaccine had been manufactured to meet UK demand but all that remained was for the vaccine to be put into vials and packaged for transport.