Brazil's Bolsonaro tests positive.
https://www.bbc.co.uk/news/world-latin-america-53319517
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Brazil's Bolsonaro tests positive.
https://www.bbc.co.uk/news/world-latin-america-53319517
half way down page two of the forum....seems things are getting back to normal
https://newsakmi.com/news/world/uk-n...ce-system/amp/
somehow we've spent 10 billion on a track and trace system that doesn't work.
Ireland have theirs up and running and cost a fraction of that.
I wonder where that 10bn is now.
:facepalm:Quote:
Originally Posted by Rjk
A triumph of dogma over common sense?
https://www.theguardian.com/world/20...me-sources-say
Quote:
Originally Posted by the other bob wilson
Probably a good decision as we would be last in the queue for distribution as an ex-member state. Also Germany, France and Holland have already committed to purchase 400m doses of the AZ vaccine and this will be folded into the EU numbers.
Knowing a bit about the European medicines supply chain and regulatory issues around licensing of new products I reckon we are better doing our own thing
Fair enough, I can see that we could be low down the queue so to speak if any vaccine was effective - that's why I added the question mark, as it's hardly a subject I know much about.Quote:
Originally Posted by lisvaneblue
I know a bit about the regulatory requirements as well, why do you think we are better doing our own thing?Quote:
Originally Posted by lisvaneblue
if we had different regulatory requirements to the EU then nobody is going to target our market first, they would go for the EU first then look at what they would need to do to launch in the smaller markets afterwards
Assuming no deal Brexit we will have different licensing and MHRA will be responsible for approval new medicines and issuing MAs. The UK gov is setting about streamlining the UK approval process so it may be that we give approval for Covid vaccines ahead of the EU. EMA will no longer be in control of UK.Quote:
Originally Posted by Rjk
Pharma will launch first in markets that give earliest approvals. They will also have a commitment to pre-orders as and when approval is granted. UK is an attractive market as it is a reference point for many countries for approvals and price.
Also the manufacture and distribution will be phased, it's not as if they will drop 400m doses off at a warehouse in Germany.
that's simply not true, every project I've ever worked on the launch markets have been EU or USA or both. any smaller markets no matter how easy their regulatory approvals always follow on after the biggest markets are launched.Quote:
Originally Posted by lisvaneblue
next in priority would be Japan, China, Brazil etc.
https://www.theguardian.com/politics...ut-open-tender
Good to see Boris, Gove, Cummings & co cutting out the bureaucracy of the civil service in order to combat Covid19.
Nothing to see here.
:biggrin:
Pubs in Wales not permitted to open until 08 August at the earliest. He is determined to destroy the hospitality industry completely.
Parochial methodist minded reactionary!!!!
Don't worry, they can pay for it out of taxing nurses to take covid tests. I sometimes wonder if the NHS did too good a job looking after some people.Quote:
Originally Posted by Jordi Culé
Well I ran the commercial side of the UK division of a large Pharma company and maybe I got it wrong for 30 yearsQuote:
Originally Posted by Rjk
Me too. Especially as I had Boris in our ‘Celebrity Dead Pool’ syndicate. I would’ve won the pot.:frown:Quote:
Originally Posted by CCFCC3PO
I'm just speaking from my experience, if the regulatory route for the UK diverges from the EU then it is more likely that it will delay launches here rather than accelerating them.Quote:
Originally Posted by lisvaneblue
https://www.bbc.co.uk/news/uk-politics-53361167
Can anyone else see a theme developing here?
Where did you get this from?Quote:
Originally Posted by xsnaggle
Its the 13th outdoors. 3rd August indoors isnt it.
Good decision not to open 6am on a Saturday as well.
Saying that only a complete bufoon would do that.
Ok, but Im not sure your experience relates to new research based prescription medicines. They are generally not launched on an EU wide basis. Currently the EMA approves such medicines for EU. However, that is just the first hurdle.Quote:
Originally Posted by Rjk
The medicines then have to be authorised for use by individual countries.. in our case in UK by NICE. Other countries have their own methods of putting products on an approved list. Then there is the matter of pricing. Unlike non prescription medicines each EU country can set an acceptable price for prescription medicines through negotiation with the manufacturer. In UK this is done via a system agreed between Pharma industry and government.
There are a lot of other variables that I won't go into now. Suffice to say that there is currently free movement of prescription medicines across EU but not free pricing, and this can lead to supply issues as traders move goods from a lower price country to a higher price one.
So, in my experience prescription medicines are launched to each individual EU country at variable times. From discovery the patent clock is ticking and Pharma does not wait, as you implied, in order to launch in bigger markets first. So you are wrong in thinking we would delay launch in UK because EU is a bigger market
you are just talking about the commercial agreements, whereas I was talking about regulatory approvals which is where the biggest impact will be of divergence from Europe.Quote:
Originally Posted by lisvaneblue
No I'm not. Im talking about getting individual country approvals following regulatory approvals. Commercial agreements are the next level down from country approvals and often there are no commercial agreements beyond the list price.Quote:
Originally Posted by Rjk
Have you really had experience at launching prescription medicines??
some yes, more so in medical devices. it's the just the "first hurdle" bit that's the most important for me.Quote:
Originally Posted by lisvaneblue
I'm sure. you're absolutely right that once regulatory approval is obtained for a new drug then country approvals will be pursued in many countries all at once.
if the UK has different regulatory requirements then there is a real risk that the EU and USA will be considered first and the UK amongst the follow up countries.
Happy to agree to disagree though.
Quote:
Originally Posted by Rjk
Rjk....this business was my bread and butter for many years, and I have to tell you that you are wrong.
Lets leave it at that otherwise we'll be discussing forever, and currently I'm more interested in tonight's match against Fulham
French bus driver dies following attack by passengers who refused to wear masks
https://www.theguardian.com/world/20...sed-wear-masks
Sickening.
I feel so sorry for the people who have to enforce this stuff - barstaff, shop staff, bus drivers. People who aren't paid a great deal anyway having to make people do something they don't want to do, it's unfair (and I say that as someone who is pro masks)Quote:
Originally Posted by jon1959
So, immunity short lived, virus on the rise in the US, UK likely to allow US travellers into the country ahead of winter, economy in decline, 45,000 (at least) dead - which part of Johnson's plan worked best?
where have you got this from?Quote:
Originally Posted by CCFCC3PO
Twitter that bastion of truth and unbiased opinionQuote:
Originally Posted by the other bob wilson
What's untrue factually about what that video says? You can argue about the slant being put on those facts, but I think the chronological events described happened as they say they did.Quote:
Originally Posted by Elwood Blues
I was being a bit mischevious Bob.Quote:
Originally Posted by the other bob wilson
It's not the video itself it is some of the dross that inevitably becomes attached to such a thread I was commenting.
Had a quick glance at the video itself ( I've seen this stuff so many times now I couldn't face going through it again at the moment ) and I agree it seems factually and chronologically correct.
As you say though it is the slant that is put on it.
And what is left out.
Oh I can remember what was left out Elwood. Boris Johnson, Matt Hancock and Dominic Cummings all contracted the virus by not following their own advice to the letter. It's not "led by donkeys' it's led up the garden path by dishonest cretins'Quote:
Originally Posted by Elwood Blues
Do you know how they caught it then?
They obviously caught it by socially distancing, not getting basics like haircuts for 3 months (notice all MPs seem to have hair that refuses to grow), by refusing to shake hands with covid sufferers and by refusing to have anyone in their home, and refusing to go to anyone's home.Quote:
Originally Posted by Elwood Blues
Cummings was so adept at not catching it, he drove the length of England to demonstrate that, although he could catch it, noone else could get it from him - well noone of any importance anyway.
Johnson was so thankful at being kept alive that he decided it would be fitting to charge NHS staff to park at hospitals again.
Hancock was so pleased at being able to applaud the NHS that he still refuses to talk about proper remuneration for NHS staff.
Shielding to be be paused from August 16 if things continue as is.....interesting.
Yes I doQuote:
Originally Posted by Elwood Blues
apparently Wales gave England more than 10 million pieces of PPE
https://www.expressandstar.com/news/...ring-pandemic/
Do tellQuote:
Originally Posted by Dorcus
Please ( I'm being polite today - make the most of it!)
They caught it by refusing to comply with the medical advice at the time, e.g. do not shake hands with masses of people just for cheap photo ops Mr Johnson... how's that for starters?Quote:
Originally Posted by Elwood Blues
I see the UK death rate is staying below 100 on a day to day count. That must be good news.
Considering the 'expected' spike from all those people on beaches several weeks ago and people mingling in English pubs there doesn't seem to have been one, and the incubation period is come and gone.
Seems like things may be better than people thought.