Originally Posted by
lisvaneblue
I used to work at Pfizer and was involved with supply chain. My take is that the vaccine will be made at various Pfizer plants around he world. Europe will be served by the plant at Puurs, Belgium. It will be transported in specialist boxes with dry ice at -70 in quantities of up to 1000 vials. In these containers it is stable for 10 days, so has to be used within this time frame
No doubt much of it will be transported by plane so it could be in UK within 24-48 hours of manufacture. The low temperature storage requirement means that it will be administered from hubs rather than from doctors' surgeries.
Hospitals can usually store drugs at -2 to -8 and at that temperature the vaccine is stable for up to 5 days. Obviously if you keep opening a fridge to take some product out that could effect the temperature and consequently the stability.
The 5 days stability in fridge is part of the 10 day time limit, not additional to it.
So in UK we need a well orchestrated campaign to get the product from Puurs to UK hubs from where mass vaccinations can take place. The government has appointed a Tsar for England to oversee the logistics of this. It may be difficult but its certainly manageable. Same will probably apply to USA. The stability/ transport issues means the vaccine is unlikely to be suitable for some poorer countries.
A downside in UK is the devolved 4 nation approach to healthcare. Each home country will be responsible for distribution and administration once they receive supply from UK Government. Based on past experience each country will want to do things slightly differently. This just adds to the links in the supply chain and takes up valuable time. If ever there was a time for a centralised UK approach this is it.