Mark Drakeford says there has been an "overwhelming response" from Welsh companies offering to make personal protective equipment (PPE).
"We have had almost 1,000 enquiries and offers to date, half of these have been about PPE or medtech," the first minister said.
"We can’t simply rely on supplies from overseas – we have to have a homegrown supply of essential equipment.
"As part of our ongoing efforts to build up local businesses to make more of the everyday goods we use in Wales, we’ll be looking at how we can make more of the PPE we need closer to home".
"For the first time, we are self-sufficient in scrubs in Wales – we’re making 5,000 a week, bringing back overseas jobs and anchoring them in our Welsh economy."
"We have been very fortunate that we’ve had enough PPE in Wales but two items – masks and fluid-resistant gowns – are under the most pressure."