Reply With QuoteJust in case someone say its crap its in the Daily MailOriginally Posted by TWGL1
https://www.frontiersin.org/articles...22.834808/full
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Just in case someone say its crap its in the Daily Mail
https://www.frontiersin.org/articles...22.834808/full
They will keep coming these kind of reports …. and the less outlandish they appear
A BLAST search for the 12-nucleotide insertion led us to a 100% reverse match in a proprietary sequence (SEQ ID11652, nt 2751-2733) found in the US patent 9,587,003 filed on Feb. 4, 2016 (10) (Figure 1). Examination of SEQ ID11652 revealed that the match extends beyond the 12-nucleotide insertion to a 19-nucleotide sequence: 5′-CTACGTGCCCGCCGAGGAG-3′ (nt 2733-2751 of SEQ ID11652), such that the resulting mRNA would have 3′- GAUGCACGGGCGGCUCCUC-5′, or equivalently 5′- CU CCU CGG CGG GCA CGU AG-3′ (nucleotides 23547-23565 in the SARS-CoV-2 genome, in which the four bold codons yield PRRA, amino acids 681–684 of its spike protein). This is very rare in the NCBI BLAST database.
Mate! can you break this down for me coz i watches footie like and eats chip buttys
Not exactly breaking news though, just wondering why it took so long to reach the news outlets ?
From the link:
'Professor Lawrence Young, a virologist at Warwick University, admitted the latest finding was interesting but claimed it was not significant enough to suggest lab manipulation.
He told MailOnline: 'We're talking about a very, very, very small piece made up of 19 nucleotides.
'So it doesn't mean very much to be frank, if you do these types of searches you can always find matches.
'Sometimes these things happen fortuitously, sometimes it's the result of convergent evolution (when organisms evolve independently to have similar traits to adapt to their environment).
'It's a quirky observation but I wouldn't call it a smoking gun because it's too small.
He added: 'It doesn't get us any further with the debate about whether Covid was engineered.'
Dr Simon Clarke, a microbiologist at Reading University, questioned whether the find was as rare as the study claims.
He told MailOnline: 'There can only be a certain number of [genetic combinations within] furin cleavage sites.
'They function like a lock and key in the cell, and the two only fit together in a limited number of combinations.
'So it's an interesting coincidence but this is surely entirely coincidental.'
In the words of Organ Morgan, this appears to be a bit of a "nothin' burger"
Think this bit in the Mail report, which bizarrely didn't make its sensationalist headline tells you everything you need to know about the provenance of the claim.
Professor Lawrence Young, a virologist at Warwick University, admitted the latest finding was interesting but claimed it was not significant enough to suggest lab manipulation.
He told MailOnline: 'We're talking about a very, very, very small piece made up of 19 nucleotides.
'So it doesn't mean very much to be frank, if you do these types of searches you can always find matches.
'Sometimes these things happen fortuitously, sometimes it's the result of convergent evolution (when organisms evolve independently to have similar traits to adapt to their environment).
'It's a quirky observation but I wouldn't call it a smoking gun because it's too small.
He added: 'It doesn't get us any further with the debate about whether Covid was engineered.'
Dr Simon Clarke, a microbiologist at Reading University, questioned whether the find was as rare as the study claims.
He told MailOnline: 'There can only be a certain number of [genetic combinations within] furin cleavage sites.
'They function like a lock and key in the cell, and the two only fit together in a limited number of combinations.
'So it's an interesting coincidence but this is surely entirely coincidental.'
Just because someone offered an alternative view of the article doesn’t mean he’s correct … he’s bound to say the opposite.
Oxford Manufacturers we’re working on MhRA vaccines for years … all coincidences of course
Why would they be "bound to say the opposite"?
You posted the article and now you don't like the contents.
I’m more than satisfied with the story , and the addition article which represents pretty much the MOL headline , not the viewpoint of a person who’s on the government payroll.
Could be rubbish but it’s plausible
I'm incredibly confused.
Who are you referring to?
The people quoted in the article are a Virologist from Warwick University and a Microbiologist from Reading University.
Of course basically :
A BLAST search for the 12-nucleotide insertion led us to a 100% reverse match in a proprietary sequence (SEQ ID11652, nt 2751-2733) found in the US patent 9,587,003 filed on Feb. 4, 2016 (10) (Figure 1). Examination of SEQ ID11652 revealed that the match extends beyond the 12-nucleotide insertion to a 19-nucleotide sequence: 5′-CTACGTGCCCGCCGAGGAG-3′ (nt 2733-2751 of SEQ ID11652), such that the resulting mRNA would have 3′- GAUGCACGGGCGGCUCCUC-5′, or equivalently 5′- CU CCU CGG CGG GCA CGU AG-3′ (nucleotides 23547-23565 in the SARS-CoV-2 genome, in which the four bold codons yield PRRA, amino acids 681–684 of its spike protein). This is very rare in the NCBI BLAST database.
This is why we need the Daily Mail to perform these tedious tasks for us so we can eat our chips and watch the footy
I'm equally bemused. The scientist's work are interpreted by the Daily Mail as there are no direct quotes from the team. As much as I can discern from the scientific study LoM helpfully posted to add weight to the headline, the most the study says is that they found something strange that warrants further investigation.
The Mail, which has long plugged the Virus was man-made theory, seemingly can't find any scientist to support the headline and the two who they were able to quote were tepid at best. The rest of the article is a rehash of things they've posted before.
I can't understand, if as the OP states, the scientists quoted were in cahoots with the Government, so they would say that wouldn't they, why the government is trying to play down articles critical of the Chinese. Surely that would be a perfect deflection from their response to the crisis?
As we move forward I'm guessing more and more will be revealed, the trouble we have China is such a very closed society and depending on what scientist evaluate form the findings they have they will deliver a varied output , they are a very split community .
and you call yourself a Cardiff city fan. You're talents are wastedOf course basically :
A BLAST search for the 12-nucleotide insertion led us to a 100% reverse match in a proprietary sequence (SEQ ID11652, nt 2751-2733) found in the US patent 9,587,003 filed on Feb. 4, 2016 (10) (Figure 1). Examination of SEQ ID11652 revealed that the match extends beyond the 12-nucleotide insertion to a 19-nucleotide sequence: 5′-CTACGTGCCCGCCGAGGAG-3′ (nt 2733-2751 of SEQ ID11652), such that the resulting mRNA would have 3′- GAUGCACGGGCGGCUCCUC-5′, or equivalently 5′- CU CCU CGG CGG GCA CGU AG-3′ (nucleotides 23547-23565 in the SARS-CoV-2 genome, in which the four bold codons yield PRRA, amino acids 681–684 of its spike protein). This is very rare in the NCBI BLAST database.
This is why we need the Daily Mail to perform these tedious tasks for us so we can eat our chips and watch the footy
In fairness it was one of his more understandable posts.
[QUOTE=ToTaL ITK;5278685]and you call yourself a Cardiff city fan. You're talents are wasted[/QUOT
There every home game, wind, rain or nuclear war, with chips , half a cider , and Daily Mail for half time chuckles.
Never argue with the fact checkers!
Nothing to see here. Move along!
In evolutionary terms, which came first Delta or Omnicron?
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