I live in Lodz which is a 14 hour drive from Calais, non toll motorway all the way, with 3 short breaks. I’ve done it 4 times so far.
Calais, Antwerp, Eindhoven, Rhine valley, Hanover 1/2 way, Berlin, Poznań.
Warsaw is about an hour beyond Lodz.

I don’t know the south route but Calais to Wroclaw must also be around 14 hours. Wroclaw to the Ukrainian border must be another 3 to 4 hours but I haven’t done it for over ten years.

The last time I stayed in the Holiday Inn in Ashford & caught the 6:30 train and got to my house around 21:30. Drop me a message if you want anyone info.