Coronavirus update - NO MORE RESTRICTIONS

[goats]

Re: Coronavirus update

All this talk of corona Christmas on the news, I’m absolutely buzzing at the fact we won’t be seeing the in laws for the first time in 10 years, no travelling, just me the wife and kids....if there was ever a silver lining this is surely it. Anyone else in the same heartbreaking predicament?

[the other bob wilson]

Re: Coronavirus update

News of a "nearly 95 per cent" effective vaccine now;-

https://www.bbc.co.uk/news/health-54902908

[Rjk]

Re: Coronavirus update

News of a "nearly 95 per cent" effective vaccine now;-

https://www.bbc.co.uk/news/health-54902908

that seems like more promising news, especially that it can be stored in a fridge for upto a month, far more realistic to be able to roll this out than the Pfizer one.
I wonder if Pfizer realized that their offering would never be taken up without significant infrastructure in place to be able to deliver it at temperature, so they released their trial results first to try to get public pressure to make governments put that kind of infrastructure in place.

[the other bob wilson]

Re: Coronavirus update

that seems like more promising news, especially that it can be stored in a fridge for upto a month, far more realistic to be able to roll this out than the Pfizer one.
I wonder if Pfizer realized that their offering would never be taken up without significant infrastructure in place to be able to deliver it at temperature, so they released their trial results first to try to get public pressure to make governments put that kind of infrastructure in place.

You may be right, any Government which is perceived to be hesitating on a "working vaccine" on financial grounds could expect to see a pretty big dip in their ratings.

It's the fact that two vaccines of a similar type have produced virtually identical results up to now which is most encouraging in my book because you'd think any other company using the same approach would also get effectiveness percentages around the 90% mark.

[Hilts]

Re: Coronavirus update

Great news.

[lisvaneblue]

Re: Coronavirus update

that seems like more promising news, especially that it can be stored in a fridge for upto a month, far more realistic to be able to roll this out than the Pfizer one.
I wonder if Pfizer realized that their offering would never be taken up without significant infrastructure in place to be able to deliver it at temperature, so they released their trial results first to try to get public pressure to make governments put that kind of infrastructure in place.

Of course Pfizer realised there was an issue with storage which is why in parallel they devised a Pfizer cold box container to transport it at the correct temperature. The fact that it can be refrigerated for up to 5 days before use makes it manageable for mass vaccination. The specialist pharmaceutical logistic companies can handle both. I don't see that being able to store in a fridge for a month is much better than 5 days in practice.. The fridges used, say in a surgery, are not like your domestic one, they are specialist scientific ones with calibrated temperature control, usually quite small.

[Hilts]

Re: Coronavirus update

This Moderna vaccine wouldnt be available to the UK until the Spring at the earliest.

[Rjk]

Re: Coronavirus update

Of course Pfizer realised there was an issue with storage which is why in parallel they devised a Pfizer cold box container to transport it at the correct temperature. The fact that it can be refrigerated for up to 5 days before use makes it manageable for mass vaccination. The specialist pharmaceutical logistic companies can handle both. I don't see that being able to store in a fridge for a month is much better than 5 days in practice.. The fridges used, say in a surgery, are not like your domestic one, they are specialist scientific ones with calibrated temperature control, usually quite small.

Clearly this second vaccine would be more convenient in practice than the Pfizer one.

Weren't you the same guy a week or so ago who was severely criticizing Mark Drakeford for not immediately investing in loads of infrastructure to deliver the vaccines at -70C , then there were people involved in the cold delivery logistics type company saying that that would be a huge challenge as the capacity would be massively exceeded.
Something that would last for 6 months in a normal freezer and 1 month in a normal fridge would clearly be much easier to manage a large scale roll out.

[MacAdder]

Re: Coronavirus update

VHS vs Betamax.... but who'll be which

[the other bob wilson]

Re: Coronavirus update

A combination of encouraging news and not so encouraging news in Vaughan Gething's press briefing today as covered by the BBC's rolling news;-

https://www.bbc.co.uk/news/live/uk-wales-54958901

[lisvaneblue]

Re: Coronavirus update

Clearly this second vaccine would be more convenient in practice than the Pfizer one.

Weren't you the same guy a week or so ago who was severely criticizing Mark Drakeford for not immediately investing in loads of infrastructure to deliver the vaccines at -70C , then there were people involved in the cold delivery logistics type company saying that that would be a huge challenge as the capacity would be massively exceeded.
Something that would last for 6 months in a normal freezer and 1 month in a normal fridge would clearly be much easier to manage a large scale roll out.

yes I was critical of Mark Drakeford. At the time none of us knew that Pfizer had addressed the transportation issue, nor that it was stable for 5 days in a fridge ( not a 'normal fridge' but a specific clinical standard fridge, as the others would be as well). In practice the Pfizer one should not be an issue for us in UK.

I think other vaccines that appear more stable might be better deployed to warmer countries or those parts of the world where 'cold chain' transport might be more difficult

Any how the Moderna vaccine is unlikely to be available in UK anytime soon as we in UK haven't ordered so the Pfizer one may have to do

[goats]

Re: Coronavirus update

Of course Pfizer realised there was an issue with storage which is why in parallel they devised a Pfizer cold box container to transport it at the correct temperature. The fact that it can be refrigerated for up to 5 days before use makes it manageable for mass vaccination. The specialist pharmaceutical logistic companies can handle both. I don't see that being able to store in a fridge for a month is much better than 5 days in practice.. The fridges used, say in a surgery, are not like your domestic one, they are specialist scientific ones with calibrated temperature control, usually quite small.

Exactly, five days is plenty....

[Croesy Blue]

Re: Coronavirus update

The AZ/Oxford vaccine would be the best news for us, if that has a similar efficiency we will be sorted quite quickly. Results before the end of the month on that one I hope.

[Croesy Blue]

Re: Coronavirus update

Exactly, five days is plenty....

Isn't it more to do with the pfizer one needing to be stored at a much lower temperature than this one and the AZ one?

[Rjk]

Re: Coronavirus update

Exactly, five days is plenty....

5 days probably means you have to do weekly deliveries everywhere that the vaccine needs to get to, as most won't have the capability to store at -70
A month at "fridge" temperatures means you can store more at each location and only deliver every few weeks, it makes the logistics much easier doesn't it?